ADL: Vina Question

Arjun Subramaniam arjunsubway at
Mon Feb 10 21:32:48 PST 2014


I am a high school student who is conducting biological research at
Stanford, and I am hoping to use computer simulations to augment the
biological work. Thanks for creating such a great software - It really is

One question - How do we analyze the results? I seem to be given a list of
modes and the binding affinities and rmsd values of each mode, but I don't
quite know what they mean. Are negative binding affinities like -10
indicative of better or worse ligand-receptor binding than values like -4,
or is it specific to each situation? And if it is specific to each
situation, how do we figure out how good the binding affinity is?

Thank you,

Do or do not. There is no try - Master Yoda

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